Glass ionomer cements are the most commonly used tools to ensure the remineralisation of dental tissues after caries removal, as failure to do can result in the progression of bacteria to the pulpal chamber. Clinically minimally invasive treatments use these glass ionomer cements yet they have no therapeutic ability to bio-remineralise the partially demineralised caries-affected dentine.
Salvatore Sauro, Professor of Dental Biomaterials and Minimally Invasive Dentistry, said “the most important problem related to dental fillings in demineralised dental tissues, such as caries-infected dentine, is the lack of therapeutic bio-remineralisation which can extend the durability of the resin-dentine bonding interface created with dental adhesives and resin composites.”
Researchers from CEU Cardenal Herrera University have found an alternative to glass ionomer cements which uses phosphoproteins’ biomimetic analogues in combination with experimental bioactive resin-based dental adhesives. This combination allowed the biomechanical properties of the demineralised dentine, such as the elastic modulus and hardness, to completely recover and this is being hailed as a revolutionary step in the process.
Prof Sauro and his colleagues have also shown that introducing calcium and phosphates to bioactive adhesive resin-based materials in combination with analogues of phosphoproteins can improve the longevity of the adhesion of dental composite restorations to dental tissues. This, again, allows for the biomimetic remineralisation of mineral-depleted dentine at the bonding interface.
The results of Prof Sauro’s latest study was published in Dental Materials